Learning Health System (also Learning Healthcare System; LHS)

In a learning health system information generated from patients within a system is continuously analyzed to improve patient care. In LHSs, researchers and clinicians analyze various types of health information, including data from clinical visits, laboratory results, medical imaging, and genomic profiling, to gain an understanding of disease processes and how medical interventions affect disease outcomes. The goal is to use these analyses to make increasingly individualized patient care decisions.


Institute of Medicine. (2007) “The Learning Healthcare System: Workshop Summary (IOM Roundtable on Evidence-Based Medicine.”  Link to IOM report

Greene SM, Reid RJ, and Larson, EB. (2012) “Implementing Learning Health System: From Concept to Action.” Ann Intern Med, 157(3):207-210. Link to abstract

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