Genomics and Drug Discovery
In the New York Times, Dan Hurley reports on how using genomics (the study of genes and their functions) to discover drugs has failed to live up to expectations. The article outlines the challenges facing the genomics-based approach, including the sheer complexity of human biology and the fact that many diseases are caused by multiple genetic variants. Alternatively, the old-fashioned approach to drug discovery, where observations of molecular behavior in organisms are used, still holds promise, especially when aided by novel molecular engineering technology. The complete article can be found here.